To aminoglycosides II generation is also tobramycin, similar in properties and applications with gentamicin. For example, tetracyclines, suppressing the normal gut can cause intestinal candidiasis. Aminoglycosides III generation amikacin, netilmicin similar to the spectrum of action, interaction with gentamicin and tobramycin; differ effective against bacteria resistant to aminoglycosides, I and II generations. So, tetratcycline can disrupt the function of the liver, aminoglycosides cause hearing loss and vestibular disorders, chloramphenicol, shows you breach the blood system, etc. As a result, in the place And join other amino acids are formed "Wrong" (non-functional) proteins. Therefore, their use in mostly local infection in the eyes, ears, skin. Dysbacteriosis develops in antibiotic suppression of the normal micro-flora of the body. Polar compound. Aminoglycosides are used mainly for severe infections caused by susceptible micro-organisms to aminoglycosides (Sepsis, peritonitis, urinary tract infections, pneumonia, wound and burn infection). Well pro-arise in the bone tissue. Streptomycin is effective against cocci, beckon klebsi-ell, agents of tularemia, plague, brucellosis, beckon Apply streptomycin in tuberculosis, tularemia, plague (with the Doxey-cyclin), and brucellosis. Other side effects: stomatitis, glossitis, nausea, vomiting, diarrhea, rash, optic neuritis, encephalopathy. Used topically for treatment of infected cuts, scrapes, and burns. Violate the initial stages of protein synthesis on the ribosomes of bacteria: education policy and the correct reading of the mRNA. Drug is prescribed orally 4 times a day in severe cases, but is administered intravenous. Chloramphenicol was appointed beckon and in severe cases, intravenously. Enter drug intramuscularly or intravenously (slowly Peritonsillar Abscess drip). Externally as an ointment beckon is used in pyoderma, infected wounds, eye (in the form Fetal Scalp Electrode eye drops ointment) - with blepharitis, conjunctivitis, keratitis. In the form of eye ointment is used for blepharitis, beckon Roksitromitsin (rulid) and clarithromycin, in addition, is prescribed for ulcer-term disease of the stomach and duodenum for eradication of H. In addition, the action-Aminogen likozidov disturbed permeability cytoplasmic membrane of bacteria. Intramuscularly or intravenously drip. Through chi-toplazmaticheskuyu membrane of bacteria penetrate through oxygen-dependent active transport (and therefore ineffective against anaerobic bacteria). Therefore, at start-Xia diarrhea receiving the drug should be discontinued. Practically not absorbed in the beckon tract, so they are administered parenterally. Rifampicin appointed interior and intravenously, primarily as a means berkuleznogo protivotu-I series, as beckon as in the treatment of brucellosis and other diseases caused by microorganisms sensitive to rifampicin (pneumonia, pyelonephritis, osteomyelitis). Chloramphenicol inhibits hepatic microsomal enzymes and, therefore, may exacerbate the effects of drugs, which are inactivated by these enzymes. Lincomycin is less active and often causes side effects. At the most sensitive microorganisms’ macrolides act tank teriostaticheski. Act on the gram-negative bacteria: E. If ingestion is practically not absorbed in the gastrointestinal tract and can be applied to pseudomembranous colitis. Unlike the person who receives folic acid from food, the body naturally mikroor synthesize folic acid, necessary for the formation of purines, pyrimidines and synthesis of DNA and RNA. Well into the cells of the body infected by bacteria. The reaction of exacerbation is possible with quick action of bactericidal antibiotics ticks. Chance of pseudomembranous colitis associated with Gymnasium of normal intestinal microflora Niemi (strong abdominal cramping, diarrhea, bloody stools). Aminoglycosides - Dehydroepiandrosterone Sulphate antibiotics. Effective in relative shenii Mycobacterium tuberculosis. Side effects of rifampicin: flu-like syndrome, disorders of the function of liver and kidney, ataxia, blurred vision, disturbances menstrual cycle, skin reactions, red-brown staining of the lacrimal fluid, sweat, urine. The drug is not absorbed in the gastrointestinal tract, it can appoint inside with enteritis, as well as to suppress the microbial flora of intestinal ne-ed surgery. Linkozamidov side effects: nausea, vomiting, diarrhea, liver damage, skin rashes, neutropenia, thrombocytopenia. In 1939 G Domagk (Germany) won the Nobel Prize for his discovery of anti-bacterial effect of prontosil and beckon . Neomycin is more toxic, is used only locally. Erythromycin is used in pharyngitis, diphtheria, pneumonia, prostatitis, caused by chlamydia, ureaplasma, and syphilis, if benzylpenicillin not apply, for the prevention of pertussis.
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