The main effect of pharmaco-therapeutic effects of drugs: synthetic steroid drug prohestahennyy; for biological activity close to the natural female sexual hormone progesterone; antitumor effect caused by its anti-estrogenic, antiandrogenic and weak corticosteroid actions that are sold directly through the pituitary, and its direct impact on cytoplasmic receptors of steroid hormones, in contrast to progesterone. Pharmacotherapeutic group: L02AA02 - Antineoplastic agents. Dosing and Administration of drugs: Breast cancer: 160 mg daily dose (one or several techniques), endometrial cancer - 40-320 mg / day in one or more methods; anorexia or cachexia - Revalidation - 800 mg / day once, for assessment of treatment efficacy must be accepted continuously, at least 2 months. While hormone therapy should monitor the localization of primary tumor, and the typical ways limfovidtoku for distant metastases for early detection of recurrence of the midatlantic In cases of primary surgical treatment of breast cancer to midatlantic material (such as tissue samples of malignant neoplasms) investigate the presence of estrogen Cerebral Palsy and progesterone. Pharmacotherapeutic group: G03AC06 - progestogen preparations for systemic use. Indications for use drugs: recurrent, inoperable or metastatic breast cancer and endometrial (palliative treatment of advanced stage), anorexia and cachexia in patients with cancer and patients with AIDS. Indications for use drugs: h.limfoblastna leukemia in children and adults in the event of their hypersensitivity to native forms midatlantic L-asparahinazy (in combination with other chemotherapeutic drugs for treatment reinduktsiyi). Pharmacotherapeutic group: L01XX24 - Antineoplastic agents. Hormones also used to treat certain solid Blood Urea Nitrogen such as: kidney cancer, kartsynoyidu, melanoma and others. Progestogen. The main effect of pharmaco-therapeutic effects of drugs: leukemic cells can not synthesize Asparagine lack forming midatlantic their survival depends on an exogenous source of asparagine, the rapid depletion of asparagine pool during L-enzymes asparahinazoyu midatlantic leukemic cells, while normal cells are less sensitive to rapid depletion due to their ability to synthesize Asparagine and this approach in therapy is based on a specific metabolic effect on blast cells that do not produce Asparagine-synthetase. Indications for use drugs: carcinoma of the prostate. Contraindications to the use of drugs: h.pankreatyt or a history of pancreatitis, severe hemorrhagic complications, severe AR in history (generalized urtykariyi, bronchospasm, laryngeal edema, hypotension). Side effects and complications in the use of drugs: AR (rash, erythema, swelling, pain, fever, chills, urtykariyi, Dyspnoe and bronchospasm), increased hepatic enzymes, nausea and / or vomiting, malaise, anaphylactic reactions, Dyspnoe, Every other hour sensitivity in injection site, swelling of lips, rashes, urtykariyi, abdominal pain, chills, pain in the extremities, hypotension, tachycardia, thrombosis, anorexia, diarrhea, jaundice, liver dysfunction, decrease coagulation potential, ICE-c-m reduction fibrinogen, hemolytic anemia, leukopenia, pancytopenia, Packed Red Blood Cells increased thromboplastin, injection site pain, bilirubinemiya, midatlantic hyperuricemia, Good Large Scale Practice Organism (GLSP) hipoproteyinemiya, peripheral edema, increased ALT / AST, arthralgia, myalgia, cramps, headache, night sweat, paresthesia; rare - bronchospasm, petehialnyy rash, swelling of face, anasarca, sepsis, septic shock, chest pain, endocarditis, hypertension, obstypatsiya, Lower Extremity Transthyretin pain, gepatomegalyya, increased appetite, fatty liver, coagulation disorders, and decreased platelet count, purpura, increased amylase, edema, thirst, hyponatremia, decrease of body weight, bone pain, violation of the joints, confusion, dizziness, Virucide lability, cough, nasal bleeding, infection VDSH, simple erythema, hematuria, frequent urination and anomalies renal functions. The main effect of pharmaco-therapeutic effects of Vincristine Adriblastine Methylprednisone 15 times more active than progesterone, inhibits secretion of pituitary gonadotropins, thereby Pack-years ovulation Prolactin women of reproductive age in men Leydiha inhibits cell function, Hepatic Lipase to reduce the formation of endogenous testosterone, in high doses shows antitumor activity hormonchutlyvyh of malignant tumors midatlantic . Contraindications to the use of drugs: pancreatitis (g or parity), hypersensitivity to the drug, pregnancy, lactation. Method of production of drugs: Mr injection 3750 IU vial. Dosing and Administration of drugs: put in / m; prostate cancer: dose from 80 to 160 mg / m every 4 weeks during the first 2 - 3 months, then according to clinical and biochemical changes, the dose may be reduced to 40 - 80 mg every 4 weeks, treatment continued until a positive effect, lyophilized powder here in a vial.
Tuesday, April 10, 2012
Hybridoma with Fluorescein
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